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Two side effects were modestly more common than placebo headache (20% vs 12%) and lightheadedness (19% vs 12%) and these are almost entirely the diuretic effect (mild dehydration plus a slight blood-pressure drop)

or cancer excluding basal or squamous cell skin cancer

Opt for traditional rolled oats or steel-cut oats rather than instant varieties, which often contain added sugars and have a higher glycaemic index according to Diabetes UK guidance

Despite their FDA approval for diabetes treatment, the surge in demand for these medications for weight loss purposes eventually led to product shortages